Publications
Rolf Renne, full publication record:
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Publications Related to P01 Project (most recent first):
- Stribling D, Xia Y, Amer MK, Graim KS, Mulligan CJ, Renne R. The model student: GPT-4 performance on graduate biomedical science exams. Sci Rep. 2024 Mar 7;14(1):5670. doi: 10.1038/s41598-024-55568-7. PDF
- Chekka LMS, Tantawy M, Langaee T, Wang D, Renne R, Chapman AB, Gums JG, Boerwinkle E, Cooper-DeHoff RM, Johnson JA. Circulating microRNA Biomarkers of Thiazide Response in Hypertension. J Am Heart Assoc. 2024 Feb 20;13(4):e032433. doi: 10.1161/JAHA.123.032433. Epub 2024 Feb 14. PMID: 38353215. PDF
- Stribling D, Gay LA, Renne R. Hybkit: a Python API and command-line toolkit for hybrid sequence data from chimeric RNA methods. Bioinformatics. 2023 Dec 1;39(12):btad721. doi: 10.1093/bioinformatics/btad721. PDF
- Nanni AV, Martinez N, Graze R, Morse A, Newman JRB, Jain V, Vlaho S, Signor S, Nuzhdin SV, Renne R, McIntyre LM. Sex-Biased Expression Is Associated With Chromatin State in Drosophila melanogaster and Drosophila simulans. Mol Biol Evol. 2023 May 2;40(5):msad078. doi: 10.1093/molbev/msad078. PMID: 37116218. PDF
- Gobin C, Inkabi S, Lattimore CC, Gu T, Menefee JN, Rodriguez M, Kates H, Fields C, Bian T, Silver N, Xing C, Yates C, Renne R, Xie M, Fredenburg KM. Investigating miR-9 as a mediator in laryngeal cancer health disparities. Front Oncol. 2023 Apr 4;13:1096882. doi: 10.3389/fonc.2023.1096882. eCollection 2023. PMID: 37081981. PDF
- Goodrum, et al. Virology under the Microscope-a Call for Rational Discourse.
- mSphere. 2023 Apr 20;8(2):e0003423. doi: 10.1128/msphere.00034-23. Epub 2023 Jan 26. PMID: 36700653.
- mBio. 2023 Feb 28;14(1):e0018823. doi: 10.1128/mbio.00188-23. Epub 2023 Jan 26. PMID: 36700642.
- J Virol. 2023 Feb 28;97(2):e0008923. doi: 10.1128/jvi.00089-23. Epub 2023 Jan 26. PMID: 36700640. PDF
- mSphere. 2023 Apr 20;8(2):e0003423. doi: 10.1128/msphere.00034-23. Epub 2023 Jan 26. PMID: 36700653.
- Serfecz JC, Hong Y, Gay LA, Shekhar R, Turner PC, Renne R. DExD/H Box Helicases DDX24 and DDX49 Inhibit Reactivation of Kaposi's Sarcoma Associated Herpesvirus by Interacting with Viral mRNAs. Viruses. 2022 Sep 20;14(10):2083. doi: 10.3390/v14102083. PDF
- Gay LA, Turner PC, and Renne R. 2021. Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) to Identify MicroRNA Targets. Current Protocols, e257, vol 1, doi: 10.1002/cpz1.257. PDF
- Stribling D, Lei Y, Guardia CM, Li L, Fields CJ, Nowialis P, Opavsky R, Renne R, Xie M. 2021. A non-canonical microRNA derived from the snaR-A non-coding RNA targets a metastasis inhibitor. RNA doi:10.1261/rna.078694.121. PDF
- Kozar I, Philippidou D, Margue C, Gay LA, Renne R, Kreis S. 2021. Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells. Cancers (Basel) 13. PDF
- Gay LA, Stribling D, Turner PC, Renne R. 2021. Kaposi's Sarcoma-associated Herpesvirus microRNA mutants modulate cancer hallmark phenotypic differences in human endothelial cells. J Virol doi:10.1128/JVI.02022-20. PDF
- Jahn SC, Gay LA, Weaver CJ, Renne R, Langaee TY, Stacpoole PW, James MO. 2020. Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes. Drug Metab Dispos 48:563-569. PDF
- Yin QY, Strong MJ, Zhuang Y, Flemington EK, Kaminski N, de Andrade JA, Lasky JA. 2020. Assessment of viral RNA in idiopathic pulmonary fibrosis using RNA-seq. Bmc Pulmonary Medicine 20. PDF
- Ungerleider N, Bullard W, Kara M, Wang X, Roberts C, Renne R, Tibbetts S, Flemington E. 2020. EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape. bioRxiv doi:10.1101/2020.12.21.423766:2020.2012.2021.423766 View
- Gay L, Renne R. (2020) Human Cytomegalovirus Latency and Myelosuppression: A microRNA-Dependent Yin and Yang Regulatory Loop. Cell Host Microbe. 2020 Jan 8;27(1):8-10. doi: 10.1016/j.chom.2019.12.008. PDF
- Hoffman BA, Wang Y, Feldman ER, Tibbetts SA. Epstein-Barr virus EBER1 and murine gammaherpesvirus TMER4 share conserved in vivo function to promote B cell egress and dissemination. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25392-25394. doi: 10.1073/pnas.1915752116. Epub 2019 Dec 3. PDF
- Bullard WL, Kara M, Gay LA, Sethuraman S, Wang Y, Nirmalan S, Esemenli A, Feswick A, Hoffman BA, Renne R, Tibbetts SA. (2019) Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery. PLoS Pathog. 2019 Aug 8;15(8):e1007843. doi: 10.1371/journal.ppat.1007843. PDF
- Wang Y, Feldman ER, Bullard WL, Tibbetts SA. (2019) A Gammaherpesvirus MicroRNA Targets EWSR1 (Ewing Sarcoma Breakpoint Region 1) <i>In Vivo</i> To Promote Latent Infection of Germinal Center B Cells. MBio. 2019 Jul 30;10(4). pii: e00996-19. doi: 10.1128/mBio.00996-19. PDF
- O’Grady T, Feswick A, Hoffman BA, Wang Y, Medina EM, Kara M, van Dyk LF, Flemington EK, Tibbetts SA. (2019) Genome-wide Transcript Structure Resolution Reveals Abundant Alternate Isoform Usage from Murine Gammaherpesvirus 68. Cell Reports, 27 (13). 2019 25 June. doi.org/10.1016/j.celrep.2019.05.086. PDF
- Ungerleider N, Flemington E. SpliceV: analysis and publication quality printing of linear and circular RNA splicing, expression and regulation BMC Bioinformatics. 2019 May 8;20(1):231. doi: 10.1186/s12859-019-2865-7. PDF
- Ungerleider NA, Tibbetts SA, Renne R, Flemington EK. Gammaherpesvirus RNAs Come Full Circle. [review] MBio. 2019 Apr 2;10(2). pii: e00071-19. doi: 10.1128/mBio.00071-19. PDF
- Kara M, O'Grady T, Feldman ER, Feswick A, Wang Y, Flemington EK, Tibbetts SA. Gammaherpesvirus Readthrough Transcription Generates a Long Non-Coding RNA That Is Regulated by Antisense miRNAs and Correlates with Enhanced Lytic Replication In Vivo. Noncoding RNA. 2019 Jan 10;5(1). pii: E6. doi: 10.3390/ncrna5010006. PDF
- Ungerleider N, Jain V, Wang Y, Maness NJ, Blair RV, Alvarez X, Midkiff C, Kolson D, Bai S, Roberts C, Moss WN, Wang X, Serfecz J, Seddon M, Lehman T, Ma T, Dong Y, Renne R, Tibbetts SA, Flemington EK. (2018) Comparative analysis of gammaherpesvirus circRNA repertoires: conserved and unique viral circRNAs. Journal of Virology. 2018 Dec 19. pii: JVI.01952-18. doi: 10.1128/JVI.01952-18. PDF
- Ungerleider N, Concha M, Lin Z, Roberts C, Wang X, Cao S, Baddoo M, Moss WN, Yu Y, Seddon M, Lehman T, Tibbetts S, Renne R, Dong Y, Flemington EK. (2018) The Epstein Barr virus circRNAome. PLoS Pathog 14(8): e1007206. doi.org/10.1371/journal.ppat.1007206 PDF
- Sethuraman, S, Thomas, M, Gay, LA, Renne, R. (2018) Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs, Nucleic Acids Research, gky459, doi: 10.1093/nar/gky459 PDF
- Gay, L, Sethuraman, S, Thomas, M, Turner, PC, Renne, R. (2018) Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) Identifies Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Targets in Endothelial Cells. Journal of Virology. 2018 Mar 28. 92(8). pii: e02138-17. doi: 10.1128/JVI.02138-17. PDF
- Renne, R, Flemington, EK, Tibbetts, SA. Noncoding RNAs in gammaherpesvirus tumorigenesis. Invited opinion article in preparation for Trends in Cancer.
- O’Grady T, Baddoo M, Zhang K, Kara M, Sethuraman S, Tibbetts, SA, Renne, R, Flemington, EK. Detailed transcriptome analysis of high density genomes from two γ-herpesviruses: Kaposi’s sarcoma-associated herpesvirus and Murine gamma herpesvirus 68. In preparation.
- Sethuraman S, Gay, LA, Jain, V, Haecker, I, and Renne, R. microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus. PLoS Pathogens. 2017 July 17. doi: 10.1371/journal.ppat.1006508 PDF
- Dai L, Qiao J, Nguyen, D, Struckhoff, AP, Doyle, L, Bonstaff, K, Valle, LD, Parsons, C, Toole, BP, Renne, R, Qin, Z. Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposi's sarcoma-associated herpesvirus. Oncotarget. 2016 Feb 7. doi: 10.18632/oncotarget.7227. PDF
- Feldman, ER, Kara, M, Oko, LM, Grau, KR, Krueger, BJ, Zhang, J, Feng, P, van Dyk, LF, Renne, R, Tibbetts, SA. A Gammaherpesvirus Noncoding RNA Is Essential for Hematogenous Dissemination and Establishment of Peripheral Latency. DOI: 10.1128/mSphere.00105-15. Discussed in Editorial: Kincaid, RP and S. Sullivan. Lessons learned from in vivo studies of a viral Noncoding RNA. mSphere, 2016. PDF
- Cao S, Strong, MJ, Wang, X, Moss, W, Concha, M, Lin, Z, O’Grady, T, Baddoo, M, Fewell, C, Renne, R, and Flemington, EK. High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol. 2014 Oct 29. pii: JVI.02570-14. PDF
- Qin Z, Dai L, Trillo-Tinoco J, Senkal C, Wang W, Reske T, Bonstaff K, Del Valle L, Rodriguez P, Flemington E, Voelkel-Johnson C, Smith CD, Ogretmen B, Parsons C. Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. Mol Cancer Ther. 2014 Jan;13(1):154-64. doi: 10.1158/1535-7163.MCT-13-0466. Epub 2013 Oct 18. PMID: 24140934 PDF
- Strong MJ, O'Grady T, Lin Z, Xu G, Baddoo M, Parsons C, Zhang K, Taylor CM, Flemington EK. Epstein-Barr virus and human herpesvirus 6 detection in a non-Hodgkin's diffuse large B-cell lymphoma cohort by using RNA sequencing. J Virol. 2013 Dec;87(23):13059-62. PDF
- Feldman, ER, Kara, M, Coleman, CB, Krueger, B, Renne, R, Van Dyk, L, and Tibbetts, SA. Virus-encoded miRNAs facilitate gammaherpesvirus latency and pathogenesis in vivo. MBio. 2014 May 27;5(3). pii: e00981-14. PDF
- Qin Z, Freitas E, Sullivan R, Mohan S, Bacelieri R, Branch D, Romano M, Kearney P, Oates JC, Plaisance K, Renne R, Kaleeba J, Parsons C. Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress. PLoS Pathogens. Jan 29, 2010 Vol. 6 (1): e1000742. PMID: 20126446 PDF